Science Olympiad Protein Modeling Event
Protein Modeling is an event developed by the CBM for Science Olympiad. This event challenges students to explore protein structure/function by creating 3-dimensional models of proteins using Mini-Toobers, foam-covered wire that will hold its shape once folded.
★ RULES Clarification! ★
The official Rules for the Protein Modeling event are incorrect. As clarified at https://www.soinc.org/events/rules-clarifications, the rules should read:
1. DESCRIPTION, (edits in bold): Students will use the computer visualization and online resources to construct physical models of the CRISPR Cas9 protein and Anti-CRISPR protein that are being engineered to edit plant and animal cell genomes, and answer a series of questions about the chemistry of protein folding and the interaction of structure and function for model proteins.
THE COMPETITION Part I: The Pre-Built Model, a. (edits in bold): Participants will use the program Jmol/JSmol to visualize a model of residues 1-85 of the Anti-CRISPR protein, AcrII4A, based on the coordinate data found in the 5vw1.pdb file. The 5vw1.pdb file can be accessed for free from the RCSB Protein Databank (www.rcsb.org). Jmol/JSmol can be accessed at http://cbm.msoe.edu/scienceOlympiad/designEnvironment/prebuild.html for free.
Thank You for a little help from our friends.
We are pleased to acknowledge our several partners who make this Protein Modeling event possible. This year’s event is a formal collaboration between the MSOE Center for BioMolecular Modeling and the Protein Data Bank at Rutgers. The event is supported by a grant from National Institutes of Health's SEPA (Science Education Partnership Award) program. 3D Molecular Designs provides materials for this event, at cost – and handles the packaging and distribution of kits to teams and tournament directors.
Past Protein Modeling Events
2017-18 Event Resources
The 2017-18 Science Olympiad Protein Modeling Event focused on influenza and the key virus surface proteins that are responsible for helping the virus enter the host cell. The event also covered a history of the influenza virus as well as an overview of the virus structure.2017-18 Learning Module
2016-17 Event Resources
The 2016-17 Science Olympiad Protein Modeling Event focused on the Beery Twins and the proteins involved in the biosynthesis and subsequent signaling of the neurotransmitters dopamine and serotonin.2016-17 Learning Module
2015-16 Event Resources
The 2015-16 Science Olympiad Protein Modeling Event focused on the genome editing proteins Zinc Finger Nuclease, TALE Nuclease and CRISPR, and the amazing diseases they are being engineered to fix.2015-16 Learning Module
2012-13 Event Resources
The 2012-13 Science Olympiad Protein Modeling Event focused on Nic Volker, an incredibly resilient little boy and a team of physicians and researchers who searched for an explanation for his mysterious bowel disease.2012-13 Learning Module
2011-12 Event Resources
The 2011-12 Science Olympiad Protein Modeling Event focused on stem cells and the advancements made in reverting adult cells back into pluripotent stem cells by introducing several key proteins, including C-Myc, Sox-2, Oct-4 and Klf-4.
2010-11 Event Resources
The 2010-11 Science Olympiad Protein Modeling Event focused on influenza and the key virus surface proteins that are responsible for helping the virus enter the host cell. The event also covered a history of the influenza virus as well as an overview of the virus structure.2010-11 Learning Module
News and Publications
Congratulations to the Science Olympiad Protein Modeling Champions
RCSB PDB Newsletter, Number 50, Summer 2011.
NJ Science Olympiad Protein Modeling Results
RCSB PDB Newsletter, Number 49, Spring 2011.
Fox Television Show Partners with Science Olympiad, Episode #309.
Teaching Science Through Protein Modeling
ASBMB Today, by Tim Herman, September 2010.
RCSB PDB Education Corner, by Joan Kiely, Number 47, Fall 2010.
Congratulations to the National Protein Modeling Champions
RCSB PDB Newsletter, Number 46, Summer 2010.
NJ Science Olympiad Protein Modeling Results
RCSB PDB Newsletter, Number 45, Spring 2010.
Congratulations to the National Tournament Champions
RCSB PDB Newsletter, Number 42, Summer 2009.
New Jersey Science Olympiad: Protein Modeling
RCSB PDB Outreach and Education, Number 41, Spring 2009.
Protein Modeling at the New Jersey Science Olympiad Regionals
RCSB PDB Community Focus, Number 36, Winter 2008.
Princeton High School Students Win New Jersey Science Olympiad Protein Modeling State Finals
RCSB PDB Newsletter, Number 38, Summer 2008.
2007 New Jersey Science Olympiad
RCSB PDB Education Corner, Number 33, Spring 2007.
Protein Modeling at the NJ Science Olympiad
RCSB PDB Education Corner, Number 29, Spring 2006.
Wisconsin High School Science Olympiad Protein Modeling Event
RCSB PDB Education Corner, by Gary Graper, Number 26, Summer 2005